The Minor "G" allele is associated with:

  • Lower levels of C4 protein (R). 
  • GG has lowest levels of C4 (.18) while GT has intermediate levels of C4 (.27) (TT levels= .34) (R).  


Parent Gene: HLA-DQB, TAP2

Importance: 3
Less common allele: G = 4%
More common allele: T = 96%
My Genotype: Log In
Risk Allele: G

Disease/Trait: Complement C4 Measurement

The G allele of rs241428 is reported to be associated with Complement C4 Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Complement C3 and C4 levels (Serum level of C4).