- Normal levels of Glycogen Synthase Kinase 3 Beta (GSK3B) in the body (AA).
- Normal levels of GSK3B in the body (A).
- Possible increased levels of GSK3B in the body (G) [R].
- GSK3B is important in energy metabolism and neural cell development in the body [R].
The Minor "C" allele is associated with:
- Poorer response to antidepressants given to patients with Major Depressive disorder (MDD) [R].
- Possible increased risk of Major Depressive Disorder (MDD) [R].
- Higher levels of GSK3B cause increased the risk of developing bipolar disorder [R].
- Possible increased risk of Polycystic Ovary syndrome (PCOS) [R]. This may cause irregular menstrual cycle or no menstrual cycle at all. [R] Other symptoms may include male features (due to the production of male hormones) and difficulty getting pregnant [R].
- High levels of GSK3B could lead to Alzheimer's disease [R].
The Major "A" allele is associated with: