[PMID 19741564] Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians

[PMID 16985024] Endometrial cancer risk is associated with variants of the mismatch repair genes MLH1 and MSH2.

[PMID 19930554] Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers.

[PMID 20386703] Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.

[PMID 10978353] Recurrent germline mutation in MSH2 arises frequently de novo.

[PMID 17374836] MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.

[PMID 18325052] Implications of mismatch repair genes hMLH1 and hMSH2 in patients with sporadic renal cell carcinoma.


Parent Gene: MSH2

Importance: 1
Less common allele: C = 13%
More common allele: T = 87%
My Genotype: Log In