Mechanism:

  • T = Located in noncoding sequence of DNA [R]

  • C = Located in noncoding sequence of DNA [R]

The Minor "T" allele is associated with:

  • Decreased ability to remove genotoxic compounds [R]

The Major "C" allele is associated with:

  • Increased ability to remove genotoxic compounds [R]

rs2300181

Parent Gene: CAT

Importance: 1
Less common allele: T = 24%
More common allele: C = 76%
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