[PMID 19653082] Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn's Disease in the Japanese Population

[PMID 19776189] Dietary saturated fat modulates the association between STAT3 polymorphisms and abdominal obesity in adults

[PMID 22205606] JAK2 and STAT3 polymorphisms in a Han Chinese Population with Behcet's disease

[PMID 15935090] Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma.

[PMID 17636079] Common STAT3 variants are not associated with obesity or insulin resistance in female twins.

[PMID 18451776] Study of genetic variation in the STAT3 on obesity and insulin resistance in male adults.

[PMID 18520591] Sequence variants in host cell factor C1 are associated with Meniere's disease.

[PMID 18789715] Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease.

[PMID 20159113] Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.

[PMID 21068102] Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese.

[PMID 21310444] Mitochondrial DNA copy number is modulated by genetic variation in the signal transducer and activator of transcription 3 (STAT3).

[PMID 22095036] Independent replication of STAT3 association with multiple sclerosis risk in a large German case-control sample.

[PMID 23127549] Influence of the STAT3 genetic variants in the susceptibility to psoriatic arthritis and Behcet's disease

[PMID 23611997] JAK1, but not JAK2 and STAT3, confers susceptibility to Vogt-Koyanagi-Harada (VKH) syndrome in a Han Chinese population

[PMID 24081513] Association of single-nucleotide polymorphisms in the STAT3 gene with autoimmune thyroid disease in Chinese individuals

[PMID 24781989] Association between STAT3 gene polymorphisms and ulcerative colitis susceptibility: a case-control study in the Chinese Han population

[PMID 24864251] rs744166 Polymorphism of the STAT3 Gene Is Associated with Risk of Gastric Cancer in a Chinese Population

[PMID 26745093] Single Nucleotide Polymorphisms in STAT3 and STAT4 and Risk of Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.


Parent Gene: STAT3

Importance: 3
Less common allele: G = 35%
More common allele: C = 65%
My Genotype: Log In
Risk Allele: C

Disease/Trait: Multiple Sclerosis

The C allele of rs2293152 is reported to be associated with Multiple Sclerosis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Multiple sclerosis.