The G (minor) allele is associated with:

  • More prevalent in evening types than in morning types (R). OR=2.483.
  • Per3 doesn't work as well...changes in hydropathy index, potentially less ability to bind to some other proteins such as CKI, which is known to regulate PER protein stability.

rs228697

Parent Gene: PER3

Importance: 4
Less common allele: G = 6%
More common allele: C = 94%
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