The G/G genotype was an independent risk factor for biochemical recurrence after radical prostatectomy [R].

The G/G genotype has worse prognosis and lower survival in patients with renal cell carcinoma. The survival in patients with GG genotypes was significantly worse than in those with GT+TT genotypes [R]. 

A significant association was found between the ''G'' allele and treatment-resistant depression (TRD) in males (corrected P=0.048) but not in females [R].

The ''T'' allele significantly contributed to decreased small cell lung cancer (SCLC) risk and hence considered as the protective allele [R].

The ''TT'' genotype was associated with an increased risk (TT Vs TG + GG) by 2.86-fold (p = 0.07) for breast cancer development [R]. 



Parent Gene: BCL2

Importance: 2
Less common allele: T = 38%
More common allele: G = 62%
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