rs2267668 is linked to the PPARD gene and is known to affect aerobic physical fitness [R]. This SNP has also been associated with extreme longevity [R].

The minor allele ''G'' was independently associated with less increase in individual anaerobic threshold (P = 0.002). In addition, low skeletal muscle mitochondrial function was detected in young carriers of the ''G'' allele (P = 0.02) [R].

A/G polymorphism was associated with the polycystic ovary syndrome (PCOS) (OR = 1.24, P = 0.008) [R].

 

rs2267668

Parent Gene: PPARD

Importance: 2
Less common allele: G = 15%
More common allele: A = 85%
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