Homozygosity for the minor allele ''C'' (CC) was associated with an increased risk of skin test reactivity (STR) to American cockroach (P </= 0.03), STR to German cockroach (P </= 0.01), and having a positive IgE to German cockroach (P < 0.05) [R].

''T'' allele was associated with a significant risk of Grave's disease (GD) in both the cohorts (OR = 2·04 and OR = 1·70 for Shanghai and Xiamen Island cohorts, respectively) [R].



Parent Gene: IL12A, IL12A-2, IL12A-AS1

Importance: 4
Less common allele: C = 16%
More common allele: T = 84%
My Genotype: Log In
Risk Allele: G

Disease/Trait: Multiple Sclerosis

The G allele of rs2243123 is reported to be associated with Multiple Sclerosis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Multiple sclerosis.