rs2242480 is a SNP in the CYP3A4 gene.

The rs2242480(T) allele defines the CYP3A4*_20239G>A variant.

[PMID 21692828] The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

[PMID 21902501] Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients

[PMID 17615053] Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.

[PMID 18163429] Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.

[PMID 18504423] Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response.

[PMID 18825162] Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.

[PMID 21071160] Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.

[PMID 21199372] A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.

[PMID 22178823] [Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].

[PMID 22583563] Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore.

[PMID 25217544] Fatal Methadone Toxicity: Potential Role of CYP3A4 Genetic Polymorphism


Parent Gene: CYP3A4

Importance: 1
Less common allele: T = 42%
More common allele: C = 58%
My Genotype: Log In