The Minor "T" allele is associated with:

  • Increased risk of cardiovascular disease and coronary artery disease (R).
  • Increased risk of obesity and being overweight (R).
  • Lower levels of HDL cholesterol (TT) (R) (R).
  • Increased risk of abdominal aortic aneurisms (R). The T allele (especially TT) may be a risk factor for the disease.
  • Increased risk of developing Type 2 diabetes (R).
  • Increased risk of Atherosclerosis (R).
  • Possible slight increased risk of developing Alzheimer’s disease (R) (R). Other studies did not find this association.

The C (major) allele is associated with:

  • Increased fat intake and increased Triglycerides levels (R).


Parent Gene: ABCA1

Importance: 4
Less common allele: T = 44%
More common allele: C = 56%
My Genotype: Log In