rs2200733 is linked to the MIR297 and PITX2 genes. It is significantly associated with stroke and atrial fibrillation (AF).

A significant association between the ''T'' allele and patients with Atrial fibrillation (AF) and atrial flutter (AFL) was observed (allelic p<0.001 with OR = 2.17) [R].

Carriers of the''T'' allele had an increased risk of postoperative atrial fibrillation (AF) with preoperative β blocker (BB) (OR 1.47, for those taking a BB, and OR 1.13, for those not taking a BB) [R]. 

The ''T'' allele favored increased number of episodes of atrial fibrillation (AF) per month (pā€Š=ā€Š0.045) and larger pulmonary vein diameter (recessive model, pā€Š=ā€Š0.032) [R]. 

Patients with the CC genotype exhibited a 0.45 times higher risk of developing atrial fibrillation (AF) than those with the TT genotype (p = 0.02) [R].

Carriage of the ''T'' allele (CT or TT genotype) was more common in patients with lone (39%) than typical (25%) atrial fibrillation (AF) or controls (21%, p <0.01 for both comparisons) [R]. 

The T/T genotype and the ''T'' allele were detected more frequently in patients with AF compared to controls (13.2% vs. 2.3%, p=0.001, and 29.6% vs. 17.9%, p=0.001) in a greek population [R]. 

 

rs2200733

Parent Gene: MIR297, PITX2

Importance: 5
Less common allele: T = 25%
More common allele: C = 75%
My Genotype: Log In
Risk Allele: T, T, T

Disease/Trait: Atrial Fibrillation

The T allele of rs2200733 is reported to be associated with Atrial Fibrillation (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Atrial fibrillation/atrial flutter.

Disease/Trait: Stroke

The T allele of rs2200733 is reported to be associated with Stroke (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Stroke (ischemic).

Disease/Trait: Atrial Fibrillation

rs2200733 is associated with Atrial Fibrillation (R) . It is reported to increased association with Atrial fibrillation. No specific risk allele was identified in the study.

Disease/Trait: Ischemic Stroke

The T allele of rs2200733 is reported to be associated with Ischemic Stroke (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Ischemic stroke (cardioembolic) (CCSp).

Disease/Trait: Cardiac Embolism

The T allele of rs2200733 is reported to be associated with Cardiac Embolism . Your genotype was not identified for this SNP so we are unable to comment on your association with Ischemic stroke (cardioembolic) (CCSp).