rs2171363 is a SNP of the TPH2 gene. It may play a major role in antidepressant response.

The ''GG'' genotype was associated with reduced internalizing scores for children born in the quartile above the midpoint [R].

The ''A'' allele (p=0.001) and ''A'' containing genotypes (OR=3.40) were significantly higher in patients with borderline personality disorder (BPD) [R].



Parent Gene: TPH2

Importance: 2
Less common allele: G = 40%
More common allele: A = 60%
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