The A (minor) Allele is associated with:

  • A better response to Inhaled Corticosteroid Therapy in Asthmatics [R].
  • Worse response to leukotriene receptor antagonist (LTRA) montelukast (a non steroidal therapy that acts as an anti inflammatory agent for the bronchi) in Asthmatics [R].
  • A better response to Photodynamic Therapy (PDT) in macular degeneration subjects [R].
  • Increased risk of Diabetic Retinopathy [R][R][R].

This SNP is associated with (unknown which allele):

  • Hippocampal structure, which controls memory and emotions [R].

rs2146323

Parent Gene: VEGFA

Importance: 3
Less common allele: A = 28%
More common allele: C = 72%
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