rs2078486 is a SNP of the TP53 gene. It is significantly associated with the risk of invasive serous ovarian cancer (OR(per allele) = 1.65) [R].
rs2078486 (no reported alleles) might play a role in the susceptibility to scizophrenia (SZ) (P-value = 0.029; OR = 1.21) [R].
rs2078486 (no reported alleles) was associated with ovarian cancer [R].
Presence of one or both copies of minor allele ''A'' (AG or GG) was significantly associated with elevated lung cancer risk among older individuals (adjusted OR: 1.53), smokers (adjusted OR: 1.70), alcohol drinkers (adjusted OR: 2.41) and individuals with high indoor air pollution exposure (adjusted OR: 1.51) [R].