The Minor "G" allele is associated with:

  • Increased levels of C4 protein (R). 
  • GG had the highest levels of C4 (.41) while AG had intermediate levels of C4 (.35) (AA levels= .3) (R). 



Parent Gene: HLA-DRA, NOTCH4

Importance: 3
Less common allele: G = 14%
More common allele: A = 86%
My Genotype: Log In
Risk Allele: G

Disease/Trait: Complement C4 Measurement

The G allele of rs2071278 is reported to be associated with Complement C4 Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Complement C3 and C4 levels (Serum level of C4).