rs1946519 is a SNP of the IL18 gene. It is significantly associated with altered  IL18, TNFA, IL6, IL18/IL10 and TNFA/IL10 (cytokines) ratio levels [R].

rs1946519 (no reported alleles) is associated with recurrent spontaneous miscarriage (RSM) [R].

The ''C'' allele was associated with an increased risk of acute myocardial infarction (AMI) [R].

Women with AC+AA genotype are at relatively high risk for cervical cancer [R].

The ''C'' allele was more frequent in type 1 diabetes (T1D) patients [R].

 

rs1946519

Parent Gene: IL18

Importance: 2
Less common allele: A = 41%
More common allele: C = 59%
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