The T/C genotype was significantly associated with Alzheimer's disease (AD) compared to the T/T genotype (adjusted p=0.003, OR=2.644). The ''C'' allele conferred a higher risk of AD under the dominant genetics model (adjusted p=0.001, OR=2.719) [R].

The CT+CC genotype was associated with increased late-onset Alzheimer disease (LOAD) risk (adjusted P=.0001; OR=3.640) [R].



Parent Gene: IDE

Importance: 2
Less common allele: C = 12%
More common allele: T = 88%
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