Mechanisms:

  • T = Inhibition of CETP activity

  • C = Higher levels of CETP activity [R]

The “C” allele is associated with:

  • Lower triacylglycerol levels (Inuit population) [R]

The “T” allele is associated with:

Lower total cholesterol, lower low density lipoprotein (LDL) cholesterol, higher high density lipoprotein (HDL) cholesterol (Inuit population) [R]

 

 

 

rs183130

Parent Gene: CETP

Importance: 1
Less common allele: T = 27%
More common allele: C = 73%
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