Mechanism

  • AA: Decreased ability to repair or destory damaged DNA. [R]
  • G: Normal ability to repair or destory damaged DNA. [R]

The Minor allele “A” is associated with:

  • Increased risk for developing breast and ovarian cancers (AA) [R].

    • Because of rarity this SNP further studies have to be conducted to determine the full risk.

The Major allele “G” is associated with:

  • Normal risk for developing breast and ovarian cancers (AG and GG). [R]

 

rs1800709

Parent Gene: BRCA1

Importance: 2
Less common allele: A = 0%
More common allele: G = 100%
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