Mechanism

Decreased ability to repair or destory damaged DNA. (C) [R]

Normal ability to repair or destory damaged DNA. (T) [R]

The Minor allele “C” is associated with:

  • Increased risk for developing breast cancer (CC and CT). [R]

  • Increased risk for developing Early-onset Prostate Cancer (CC and CT). [R]

The Major allele “T” is associated with:

  • Normal risk for developing breast cancer (TT). [R]

  • Normal risk for developing Early-onset Prostate Cancer (TT). [R]

 

rs1799950

Parent Gene: BRCA1

Importance: 2
Less common allele: C = 2%
More common allele: T = 98%
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