rs1799884 is a SNP of the GCK gene. It is significantly associated with an increased risk of Type 2 diabetes (T2D).
''T'' allele was associated with higherfasting plasma glucose (FPG) (P = 3.1 x 10(-7)) in adults and adolescents [R].
''T'' allele was also associated with reduced homeostasis model assessment of beta-cell function (HOMA-B) (P=0.0015) [R].
Minor allele ''T'' was significantly associated with a higher risk of gestational diabetes mellitus (GDM) [R].