- SNP is also known as c.538G>A or G180R
- SNP in the ATP-binding cassette, sub-family C (CFTR/MRP), member 11 ABCC11 gene.
- The ABCC11 protein helps transport small molecules across apical membranes such as those in apocrine secretory cells.
The T (minor) allele is associated with:
Decreased Nipple aspiration fluid (NAF) yields in women. NAF can be used to non-invasively determine breast environment (R).
Increased dryness of earwax (R).
Shorter relapse-free survival times in lung cancer patients administered S-1 one year after the operation to remove the tumor (TT) (R).
Decreased body odor (TT) (R).