Mechanism:

  • The T (minor) allele= Decreased levels of FADS1 protein [R].
  • The C (major) allele= Increased levels of FADS1 protein [R].

The T (minor) allele is associated with:

  • Lower levels of Arachidonic acid in breast milk of mothers [R].
  •  Increased IL-5 and IL-10 levels in infants, which may increase the risk of inflammatory diseases in these infants [R] [R].
  • Possible increased pregnancy time and lighter birth weight of infant if mother has the minor allele [R].

  • Increased protection against type 1 Diabetes if alpha-linoleic acids are taken [R].

  • Increased risk of acute coronary syndrome in hypertension patients [R].

  • Possible increased risk of coronary artery disease [R].

The C (major) allele is associated with:

  • Higher levels of Arachidonic acid in breast milk of mothers [R].
  • Decreased IL-5 and IL-10 levels in infants, which may decrease the risk of inflammatory diseases in these infants [R] [R].
  • Possible decreased pregnancy time and lighter birth weight of infant if mother has the minor allele [R].

  • Decreased protection against type 1 Diabetes if alpha-linoleic acids are taken [R].

  • Decreased risk of acute coronary syndrome in hypertension patients [R].

  • Possible decreased risk of coronary artery disease [R].

rs174556

Parent Gene: FADS1

Importance: 3
Less common allele: T = 28%
More common allele: C = 72%
My Genotype: Log In
Risk Allele: T, T

Disease/Trait: Blood Metabolite Measurement

The T allele of rs174556 is reported to be associated with Blood Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Blood metabolite levels (eicosapentaenoate (EPA; 20:5n3)).

Disease/Trait: Trans Fatty Acid Measurement

The T allele of rs174556 is reported to be associated with Trans Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).

Disease/Trait: Cis/Trans-18:2 Fatty Acid Measurement

The T allele of rs174556 is reported to be associated with Cis/trans-18:2 Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).