GG (Minor):

  • Least phosphatidylcholine levels (compared to AG, AA) [R].
  • Lower FADS1/2 activity, resulting in lower conversion of linoleic to arachidonic acid [R].

AG:

  • Decreased phosphatidylcholine levels (compared to AA) [R].

AA (Major):

  • Lower FADS1/2 activity, resulting in lower conversion of linoleic to arachidonic acid [R].
  • Normal phosphatidylcholine levels [R].

 

rs174548

Parent Gene: FADS1

Importance: 5
Less common allele: G = 33%
More common allele: C = 67%
My Genotype: Log In
Risk Allele: G, G, C, G, C, C, G, G

Disease/Trait: Phospholipid Measurement

rs174548 is associated with Phospholipid Measurement (R) . It is reported to association with Metabolite levels (PC). No specific risk allele was identified in the study.

Disease/Trait: High Density Lipoprotein Cholesterol Measurement

The G allele of rs174548 is reported to be associated with High Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with HDL cholesterol.

Disease/Trait: Triglyceride Measurement

The G allele of rs174548 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides.

Disease/Trait: Blood Metabolite Measurement

The C allele of rs174548 is reported to be associated with Blood Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Blood metabolite levels (arachidonate (20:4n6)).

Disease/Trait: Albumin:Globulin Ratio Measurement

The G allele of rs174548 is reported to be associated with Albumin:globulin Ratio Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hematology traits (ALB/GLB).

Disease/Trait: Trans Fatty Acid Measurement

The C allele of rs174548 is reported to be associated with Trans Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).

Disease/Trait: Cis/Trans-18:2 Fatty Acid Measurement

The C allele of rs174548 is reported to be associated with Cis/trans-18:2 Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).

Disease/Trait: Blood Metabolite Measurement

The C allele of rs174548 is reported to be associated with Blood Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Blood metabolite ratios (arachidonate (20:4n6)/dihomo-linolenate (20:3n3 or n6)).

Disease/Trait: Dihomo-Gamma-Linolenic Acid Measurement

The G allele of rs174548 is reported to be associated with Dihomo-gamma-linolenic Acid Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid).

Disease/Trait: Delta-6 Desaturase Measurement

The G allele of rs174548 is reported to be associated with Delta-6 Desaturase Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Delta-6 desaturase activity.