Patients carrying the ''C'' allele were associated with higher breast cancer-specific mortality [hazard ratio (HR), 1.4] [R].
Women with heterozygous TC genotype exhibited higher risk to develop endometrial cancer as compared to those with their wild-type or homozygous genotypes (odds ratio 3.30 and 1.86). Individuals with CC genotype were at less risk (OR: 0.08; P=0.037) to have a non-endometrioid type as compared to those with TT genotype [R].
The heterozygous TC genotype, was differentially distributed between patients with cervical neoplasia and normal women (Hommel adjusted P = .0435). CC genotypes exhibit less tendency as compared to those with wild-type homozygotes and heterozygotes [R].
Ovarian cancer patients carrying the homozygous C/C genotype had shorter Progression-free survival (PFS) and overall survival (OS) than those carrying the T allele (T/T+T/C genotype) [R].
Patients carrying TT genotype were correlated with a greater numbers of lymph node metastases (P = 0.023) [R].