Mechanism

Improved ability to repair or destory damaged DNA.  (CC) [R]

Normal ability to repair or destory damaged DNA.  (T) [R]

The Minor allele “C” is associated with:

  • Increased risk for breast cancer (CC). [R]

  • Increased Radiation Sensitivity of the Lung (CC and CT). [R]

    • This radiation is from cancer treatment and can cause lung injury.

    • CT genotype is less sensitive when compared to CC.  

The Major allele “T” is associated with:

  • Normal risk for breast cancer (CT and TT). [R]

  • Normal Radiation Sensitivity of the Lung (TT). [R]

rs16942

Parent Gene: BRCA1

Importance: 2
Less common allele: C = 35%
More common allele: T = 65%
My Genotype: Log In