rs15895 is a SNP in the OAS2 gene. This SNP is known to effect the OAS activity and is significantly associated with the outcome of viral infections.

An increase in the ''A'' allele frequency was observed among patients with neuroinvasive central nervous system disease (CNSD), compared with patients with fever (P = .047) or fever plus meningitis (P = .044) [R1, R2].

The ''A'' allele was significantly lower in all dengue patient groups compared to the  controls (P=0.0054, Pc=0.0486, OR 0.09) [R].


Parent Gene: OAS2

Importance: 2
Less common allele: A = 14%
More common allele: G = 86%
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