TC genotype was significantly associated with age-related macular degeneration (AMD) (OR= 2.13, P=0.047) [R].

C/C genotype tended to be associated with improved progressive free survival (PFS) in cancer patients (p = 0.069) [R].

The TT genotype showed a superior rate of complete cytogenetic response (CCyR) following imatinib therapy to those with TC or CC genotype group (77% versus 61% at 12 months: P = 0.02) [R].

C/C genotype tended to be associated with improved progression-free survival (PFS) in patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer (8.0 vs. 7.1 months; p = 0.069) [R].



Parent Gene: KDR

Importance: 2
Less common allele: T = 32%
More common allele: C = 68%
My Genotype: Log In