rs1477196 is a SNP in the FTO gene. It is significantly associated with obesity .
The ''G'' allele was associated with a 1.22 (0.38) increase in BMI (body-mass index) per risk allele in the low-activity group (P =.001) but only a 0.27 (0.31) increase in BMI in the high-activity group (P =.38) (interaction P =.004). Thus it was associated with obesity in the low-activity group (OR, 1.58 for each risk allele; P=.001) but not in the high-activity group (P =.11).[R].