rs1417938 is a SNP linked to the CRP gene. It is significantly associated with the C-reactive protein (CRP) levels in the blood.

''A'' allele was associated with a reduced risk of CpG island methylator phenotype (CIMP)+ rectal tumors (OR 0.5) [R].

Fenofibrate-induced the greatest reduction in C-reactive protein (CRP) levels for TT subjects compared with TA and AA subjects (P = 0.004) [R].

A significant increase in the frequency of heterozygote A/T was seen in patients with  giant cell arteritis (GCA) (OR = 1.70; p = 0.03) [R].


Parent Gene: CRP

Importance: 2
Less common allele: A = 19%
More common allele: T = 81%
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