More recently, studies have linked rs1386494 with schizophrenia in Asian populations. In a case-control study of 289 Malaysians, the G allele was found to be enriched in schizophrenic patients. Due to the low occurrence of suicidality in the study population, the authors rule out the role of suicidal behavior in this association, supporting a more direct neurological role of this SNP. [R]

 

rs1386494

Parent Gene: TPH2

Importance: 1
Less common allele: T = 14%
More common allele: C = 86%
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