JAMA rs12777823 and rs4244285 implicated in platelet response to clopidogrel

[PMID 19706858] Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy





[PMID 23755828] Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

rs12777823

Parent Gene: CYP2C18, HELLS

Importance: 2
Less common allele: A = 24%
More common allele: G = 76%
My Genotype: Log In
Risk Allele:

Disease/Trait: Response To Platelet Aggregation Inhibitor

rs12777823 is associated with Response To Platelet Aggregation Inhibitor (R) . It is reported to association with Response to clopidogrel therapy (Amish). No specific risk allele was identified in the study.

Disease/Trait: Response To Anticoagulant

rs12777823 is associated with Response To Anticoagulant (R) . It is reported to association with Warfarin maintenance dose. No specific risk allele was identified in the study.