[PMID 18391950] Identification of ten loci associated with height highlights new biological pathways in human growth. Rs12540874 has been connected to height, birth weight, and systemic sclerosis.

[PMID 25103788] Association of the intronic polymorphism rs12540874 A>G of the GRB10 gene with high birth weight


Parent Gene: GRB10

Importance: 3
Less common allele: G = 32%
More common allele: A = 68%
My Genotype: Log In
Risk Allele:

Disease/Trait: Systemic Scleroderma

rs12540874 is associated with Systemic Scleroderma (R) . It is reported to increased association with Systemic sclerosis (IcSSc). No specific risk allele was identified in the study.