[PMID 23263486] Each copy of the minor (G) allele appears to confer reduced risk for gout based on combined data from over 140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), replicating an association reported earlier for a linked SNP in this gene.
[PMID 19503597] Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence
uric acid
concentrations.