rs12338 (no reported alleles) when combined with betal leaf chewing (Or=43.962) and/or tobacco use (OR=8.972) robustly elevated the susceptibility to oral cancer [R]. 

A significantly high frequent tumor size development was observed in hepatocellular carcinoma (HCC) patients carrying rs12338 polymorphic genotype than those carrying ancestral genotype [R]. 




Parent Gene: CTSB

Importance: 2
Less common allele: C = 40%
More common allele: G = 60%
My Genotype: Log In