rs12329760 is a SNP of the TMPRSS2 gene. It may be a prognostic indicator for prostate cancer.
The variant ''T'' allele was positively associated with TMPRSS2-ERG fusion by translocation (p = 0.05) and with multiple copies of the gene fusion (p = 0.03) in patients with prostate cancer. This gene fusion has recently been associated with an aggressive phenotype, as well as recurrence and death from prostate cancer [R].