rs12329760 is a SNP of the TMPRSS2 gene. It may be a prognostic indicator for prostate cancer.

The variant ''T'' allele was positively associated with TMPRSS2-ERG fusion by translocation (p = 0.05) and with multiple copies of the gene fusion (p = 0.03) in patients with prostate cancer. This gene fusion has recently been associated with an aggressive phenotype, as well as recurrence and death from prostate cancer [R].




Parent Gene: TMPRSS2

Importance: 2
Less common allele: T = 26%
More common allele: C = 74%
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