rs11515 is linked to the CDKN2A gene. It is significantly associated with cancer.

The CG+GG genotype was more frequent in the controls (32.65%) than in patients (15.56%), reducing the risk for sporadic medullary thyroid carcinoma (s-MTC) (OR=0.174, P=0.0075) [R].

Women carrying the CG/GG genotypes may have protective effect for the development of cervical cancer (P=0.0001, OR=0.31) [R].

The ''G'' allele was associated with no defined telomere maintenance mechanism (NDTMM) tumors and was further evaluated as a marker for reduced patient survival in glioblastoma multiforme (GBM) patients [R].

rs11515

Parent Gene: CDKN2A

Importance: 2
Less common allele: C = 10%
More common allele: G = 90%
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