rs1122608 is a SNP in the SMARCA4 gene. It is significantly associated with Heart diseases.
The minor allele ''T'' was associated with a decreased risk of ischemic stroke in the Central GeneID cohort (adjusted P adj = 2.1 × 10(-4), OR 0.61). Allele ''T'' also showed significant association with a decreased total cholesterol level (P adj = 0.013) [R].
''T'' allele was associated with a decreased coronary artery disease (CAD) prevalence [R].
Homozygote genotypes have strong protective effects on the Coronary artery disease (CAD) of (P<0.0001). In addition, GT or TT genotypes were at higher risk of three vessel involvement compared to single vessels affecting (P=0.01) [R].