rs1122608 is a SNP in the SMARCA4 gene. It is significantly associated with Heart diseases.

The minor allele ''T'' was associated with a decreased risk of ischemic stroke in the Central GeneID cohort (adjusted P adj = 2.1 × 10(-4), OR 0.61). Allele ''T'' also showed significant association with a decreased total cholesterol level (P adj = 0.013) [R].

''T'' allele was associated with a decreased coronary artery disease (CAD) prevalence [R].

Homozygote genotypes have strong protective effects on the Coronary artery disease (CAD) of (P<0.0001). In addition, GT or TT genotypes were at higher risk of three vessel involvement compared to single vessels affecting (P=0.01) [R].

rs1122608

Parent Gene: SMARCA4

Importance: 5
Less common allele: T = 14%
More common allele: G = 86%
My Genotype: Log In
Risk Allele: G, G

Disease/Trait: Myocardial Infarction

The G allele of rs1122608 is reported to be associated with Myocardial Infarction (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Myocardial infarction (early onset).

Disease/Trait: Coronary Heart Disease

The G allele of rs1122608 is reported to be associated with Coronary Heart Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Coronary heart disease.

Disease/Trait: Coronary Heart Disease

rs1122608 is associated with Coronary Heart Disease (R) . It is reported to association with Coronary artery disease or ischemic stroke. No specific risk allele was identified in the study.

Disease/Trait: Stroke

rs1122608 is associated with Stroke (R) . It is reported to association with Coronary artery disease or ischemic stroke. No specific risk allele was identified in the study.

Disease/Trait: Coronary Heart Disease

rs1122608 is associated with Coronary Heart Disease (R) . It is reported to association with Coronary artery disease or large artery stroke. No specific risk allele was identified in the study.

Disease/Trait: Large Artery Stroke

rs1122608 is associated with Large Artery Stroke (R) . It is reported to association with Coronary artery disease or large artery stroke. No specific risk allele was identified in the study.

Disease/Trait: Coronary Heart Disease

rs1122608 is associated with Coronary Heart Disease (R) . It is reported to increased association with Coronary artery disease. No specific risk allele was identified in the study.