Showed the strongest association of several SNPs in the region with early onset obesity in a study of ~1,000 Caucasians.

T = Obesity, OR=1.66 (T) and 2.76 (TT) [R] [R]

T= Severe obesity in a study of 927 Japanese patients [R].

T= Obesity and type-2 diabetes [R].

rs1121980

Parent Gene: FTO

Importance: 5
Less common allele: A = 37%
More common allele: G = 63%
My Genotype: Log In
Risk Allele: T, A, A, A, A, A, A

Disease/Trait: Body Mass Index

rs1121980 is associated with Body Mass Index (R) . It is reported to have a 0.06 unit increase on Body mass index. No specific risk allele was identified in the study.

Disease/Trait: Obesity

The T allele of rs1121980 is reported to be associated with Obesity (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Obesity (early onset extreme).

Disease/Trait: High Density Lipoprotein Cholesterol Measurement

The A allele of rs1121980 is reported to be associated with High Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with HDL cholesterol.

Disease/Trait: Triglyceride Measurement

The A allele of rs1121980 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides.

Disease/Trait: Waist-Hip Ratio

The A allele of rs1121980 is reported to be associated with Waist-hip Ratio (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist-hip ratio (EA, women).

Disease/Trait: Waist-Hip Ratio

The A allele of rs1121980 is reported to be associated with Waist-hip Ratio (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist-hip ratio (EA).

Disease/Trait: Waist-Hip Ratio

The A allele of rs1121980 is reported to be associated with Waist-hip Ratio (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist-hip ratio (EA, men).

Disease/Trait: High Density Lipoprotein Cholesterol Measurement

The A allele of rs1121980 is reported to be associated with High Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with HDL cholesterol levels (Trans-ethnic initial).