[PMID 18091754] Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.


[PMID 26215868] A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion

rs1042058

Parent Gene: MAP3K8

Importance: 3
Less common allele: C = 35%
More common allele: T = 65%
My Genotype: Log In
Risk Allele: C, A

Disease/Trait: Inflammatory Bowel Disease

The C allele of rs1042058 is reported to be associated with Inflammatory Bowel Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Inflammatory bowel disease.

Disease/Trait: Crohn's Disease

The A allele of rs1042058 is reported to be associated with Crohn's Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Crohn's disease (EA).

Disease/Trait: Crohn's Disease

rs1042058 is associated with Crohn's Disease (R) . It is reported to association with Crohn's disease. No specific risk allele was identified in the study.

Disease/Trait: Ulcerative Colitis

rs1042058 is associated with Ulcerative Colitis (R) . It is reported to association with Ulcerative colitis. No specific risk allele was identified in the study.

Disease/Trait: Inflammatory Bowel Disease

rs1042058 is associated with Inflammatory Bowel Disease (R) . It is reported to association with Inflammatory bowel disease. No specific risk allele was identified in the study.