Mechanism:

  • A=increased plasma levels of Insulin-like Growth Factor Binding Protein-3 (IGFBP3) [R].

The "A" allele is associated with:

  • Reduced risk of breast cancer in European women, based on a study of both European and East Asian women [R]. These findings have not been replicated.

The “C” allele is associated with:

  • Increased risk of breast cancer in European women, based on a study of both European and East Asian women [R]. These findings have not been replicated.

rs1019731

Parent Gene: IGF1

Importance: 2
Less common allele: A = 7%
More common allele: C = 93%
My Genotype: Log In