- Rs1004446 (G to A) is a variation downstream (not in final product) of IGF2 . IGF-2 is involved in growth and repair of cells.
- Higher IGF-2 (G) (R).
- Lower IGF-2 (A) (R).
The Minor "A" allele is associated with (lower IGF-2):
- Decreased risk of endometrial cancer (R).
The Major "G" allele is associated with: