Summary of ZBTB20
The ZBTB20 gene codes for zinc finger and BTB domain-containing 20 (ZBTB20). ZBTB20 turns genes “off” [R].
ZBTB20 is required for many processes, including [R, R, R]:
- Growth of new brain cells
- Blood sugar balance
- Postnatal (post-childbirth) growth
- Immune response activation
ZBTB20 polymorphisms may be protective against some types of cancer [R].
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Zinc finger and BTB domain-containing protein 20Alternative name(s):
Dendritic-derived BTB/POZ zinc finger proteinZinc finger protein 288
- RS139459337 (ZBTB20) ??
- RS3732481 (ZBTB20) ??
- RS9841504 (ZBTB20) ??
- RS9883949 (ZBTB20) ??
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Top Gene-Substance Interactions
ZBTB20 Interacts with These Diseases
| Disease | Score |
Substances That Increase ZBTB20
| Substances | Interaction | Organism | Category |
Substances That Decrease ZBTB20
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver.
Molecular Function:
- Transcriptional Repressor Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Dna Binding
- Metal Ion Binding
Biological Processes:
- Transcription, Dna-Templated
- Positive Regulation Of Interferon-Beta Production
- Positive Regulation Of Interleukin-6 Production
- Positive Regulation Of Tumor Necrosis Factor Production