The Function of YY1
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.
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Protein names
Recommended name:
Transcriptional repressor protein YY1Short name:
YY-1Alternative name(s):
Delta transcription factorINO80 complex subunit S
NF-E1
Yin and yang 1
- RS2766692 (YY1) ??
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Top Gene-Substance Interactions
Substances That Increase YY1
| Substances | Interaction | Organism | Category |
Substances That Decrease YY1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Four-Way Junction Dna Binding
- Transcriptional Repressor Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Enhancer Sequence-Specific Dna Binding
- Dna Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding
- Transcription Coactivator Activity
- Transcription Corepressor Activity
- Rna Binding
- Zinc Ion Binding
- Transcription Regulatory Region Dna Binding
- Smad Binding
Biological Processes:
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Double-Strand Break Repair Via Homologous Recombination
- Transcription, Dna-Templated
- Regulation Of Transcription From Rna Polymerase Ii Promoter
- Cellular Response To Dna Damage Stimulus
- Spermatogenesis
- Response To Uv-C
- Negative Regulation Of Gene Expression
- Cell Differentiation
- Cellular Response To Uv