The Function of YWHAG
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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Protein names
Recommended name:
14-3-3 protein gammaShort name:
KCIP-1Alternative name(s):
Protein kinase C inhibitor protein 1- RS17149161 (YWHAG) ??
- RS2908197 (YWHAG) ??
- RS758944 (YWHAG) ??
- RS7779014 (YWHAG) ??
- RS7789940 (YWHAG) ??
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Top Gene-Substance Interactions
Substances That Increase YWHAG
| Substances | Interaction | Organism | Category |
Substances That Decrease YWHAG
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in brain, skeletal muscle, and heart.
Gene Pathways:
Molecular Function:
- Protein Kinase C Binding
- Insulin-Like Growth Factor Receptor Binding
- Protein Kinase C Inhibitor Activity
- Poly(A) Rna Binding
Biological Processes:
- G2/M Transition Of Mitotic Cell Cycle
- Negative Regulation Of Protein Kinase Activity
- Protein Targeting
- Regulation Of Signal Transduction
- Cellular Response To Insulin Stimulus
- Regulation Of Neuron Differentiation
- Regulation Of Synaptic Plasticity
- Membrane Organization
- Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway