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  3. VIM

VIM (Vimentin)

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The Function of VIM

Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.

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Protein names

Recommended name:

Vimentin

Top Gene-Substance Interactions

VIM Interacts with These Diseases

Disease Score

Substances That Increase VIM

Substances Interaction Organism Category

Substances That Decrease VIM

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • p53
  • AP-1
  • c-Jun
  • NF-kappaB1
  • Nkx2-2
  • AREB6
  • Sox9
  • c-Myb

Tissue specificity:

Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.

Gene Pathways:

  • Apoptosis
  • Muscle contraction

Molecular Function:

  • Double-Stranded Rna Binding
  • Glycoprotein Binding
  • Identical Protein Binding
  • Keratin Filament Binding
  • Protein C-Terminus Binding
  • Scaffold Protein Binding
  • Structural Constituent Of Cytoskeleton
  • Structural Constituent Of Eye Lens

Biological Processes:

  • Astrocyte Development
  • Bergmann Glial Cell Differentiation
  • Intermediate Filament Organization
  • Lens Fiber Cell Development
  • Movement Of Cell Or Subcellular Component
  • Muscle Filament Sliding
  • Negative Regulation Of Neuron Projection Development
  • Positive Regulation Of Gene Expression
  • Smad Protein Signal Transduction
  • Viral Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CB1_001140006| class-III intermediate microfilament| CTRCT30| D623_10005269| DESMB| desmin b| EGK_19488| EH28_01845| epididymis luminal protein 113| H920_16247| HEL113| M91_19473| M959_09586| MDA_GLEAN10004584| N300_06408| N301_01535| N302_03031| N303_04174| N305_13901| N306_12595| N307_01125| N308_12510| N310_00624| N311_02571| N312_12716| N320_02776| N322_02205| N325_01901| N326_05927| N327_02637| N328_08855| N329_08532| N330_10987| N331_11442| N332_06401| N333_02822| N334_02572| N335_09701| N336_10002| N340_13024| N341_08772| PAL_GLEAN10015834| TREES_T100014391| UY3_05785| vim-a| vim-b| vime| vimentin C-terminus| Y1Q_025229| Y956_12262| Z169_14005| vim

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