The Function of VAX1
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
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Protein names
Recommended name:
Ventral anterior homeobox 1Top Gene-Substance Interactions
Substances That Increase VAX1
| Substances | Interaction | Organism | Category |
Substances That Decrease VAX1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Chromatin Dna Binding
- Rna Polymerase Ii Intronic Transcription Regulatory Region Sequence-Specific Dna Binding
- Transcriptional Repressor Activity, Rna Polymerase Ii Transcription Regulatory Region Sequence-Specific Binding
Biological Processes:
- Axon Guidance
- Brain Development
- Camera-Type Eye Development
- Negative Regulation Of Neuroblast Proliferation
- Neuron Migration
- Palate Development
- Skeletal Muscle Cell Differentiation
- Transcription, Dna-Templated