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  3. UST

UST (Uronyl 2-sulfotransferase)

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The Function of UST

Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.

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Protein names

Recommended name:

Uronyl 2-sulfotransferase

UST SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10457838 (UST) ??
  2. RS13219957 (UST) ??
  3. RS190298731 (UST) ??
  4. RS2500535 (UST) ??
  5. RS35751268 (UST) ??

Top Gene-Substance Interactions

UST Interacts with These Diseases

Disease Score

Substances That Increase UST

Substances Interaction Organism Category

Substances That Decrease UST

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • Pax-3
  • NF-kappaB1
  • RREB-1

Tissue specificity:

Widely expressed.

Gene Pathways:

  • Metabolism
  • Disease
  • Glycosaminoglycan biosynthesis - chondroitin sulfate

Molecular Function:

  • Sulfotransferase Activity

Biological Processes:

  • Dermatan Sulfate Biosynthetic Process
  • Establishment Of Cell Polarity
  • Protein Sulfation
  • Regulation Of Axonogenesis
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 2OST| A306_05617| AS27_14731| AS28_00540| CB1_000812017| D623_10021278| dermatan/chondroitin sulfate 2-sulfotransferase| H920_01172| M91_05611| M959_02358| MDA_GLEAN10007820| N300_15044| N301_01111| N302_13208| N303_06830| N305_14095| N306_03716| N307_08598| N308_11520| N309_02793| N310_07990| N320_06550| N325_03605| N328_10783| N329_07095| N331_09262| N332_05592| N333_04402| N334_14293| N339_11511| PAL_GLEAN10013988| PANDA_009304| TREES_T100011043| UA2OST| uronyl-2-sulfotransferase| uronyl 2-sulfotransferase-like protein| Y1Q_006454| Y956_06322| Z169_01890| ust

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