The Function of UST
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.
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Protein names
Recommended name:
Uronyl 2-sulfotransferase- RS10457838 (UST) ??
- RS13219957 (UST) ??
- RS190298731 (UST) ??
- RS2500535 (UST) ??
- RS35751268 (UST) ??
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Top Gene-Substance Interactions
UST Interacts with These Diseases
| Disease | Score |
Substances That Increase UST
| Substances | Interaction | Organism | Category |
Substances That Decrease UST
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Widely expressed.
Molecular Function:
Biological Processes:
- Dermatan Sulfate Biosynthetic Process
- Establishment Of Cell Polarity
- Protein Sulfation
- Regulation Of Axonogenesis