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  3. UBE4A

UBE4A (Ubiquitination factor E4A)

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The Function of UBE4A

Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

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Protein names

Recommended name:

Ubiquitin conjugation factor E4 A

UBE4A SNPs

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  1. RS502514 (UBE4A) ??

Top Gene-Substance Interactions

Substances That Increase UBE4A

Substances Interaction Organism Category

Substances That Decrease UBE4A

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • STAT1
  • Meis-1
  • STAT1beta
  • STAT1alpha
  • NF-1

Molecular Function:

  • Ligase Activity
  • Ubiquitin-Ubiquitin Ligase Activity

Biological Processes:

  • Er-Associated Ubiquitin-Dependent Protein Catabolic Process
  • Protein Polyubiquitination
  • Ubiquitin-Dependent Protein Catabolic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| G protein-activated inward rectifier potassium channel 4| A306_14304| Ab2-232| AS27_04225| CB1_000200044| E4| EH28_22626| GW7_18660| H920_07512| MDA_GLEAN10018979| N300_01388| N301_03730| N302_11188| N303_12960| N305_04184| N306_01949| N307_12552| N308_03388| N309_12850| N310_09169| N311_07269| N312_06475| N321_09174| N325_06350| N327_06012| N328_09035| N331_09635| N332_10837| N334_05111| N335_11275| N339_07375| PAL_GLEAN10009043| PANDA_017770| ubiquitination factor E 4A| ubiquitination factor E4A (UFD2 homolog)| ubiquitination factor E4A, UFD2 homolog| ubiquitination factor E4A (UFD2 homolog, yeast)| ubiquitin conjugation factor E4 A| ubox2| UFD2| UFD2b| UY3_09458| Y1Q_017874| Y956_02465| Z169_16043| ube4a

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